Bacterial uptake of aminoglycoside antibiotics

HW Taber, JP Mueller, PF Miller… - Microbiological …, 1987 - Am Soc Microbiol
… Recently, Miller and his colleagues have begun a systematic reexamination of beta-lactam
effects on streptomycin uptake by Staphylococcus aureus (123), viridans and enterococcal …

Engineering living therapeutics with synthetic biology

…, T Guo, A Sokolovska, PF Miller… - Nature Reviews Drug …, 2021 - nature.com
The steadfast advance of the synthetic biology field has enabled scientists to use genetically
engineered cells, instead of small molecules or biologics, as the basis for the development …

Linezolid, the first oxazolidinone antibacterial agent

…, SJ Brickner, MC Noe, PF Miller - Annals of the New York …, 2011 - Wiley Online Library
Linezolid (Zyvox™) is the first member of an entirely new class of antibiotics to reach the
market in over 35 years; it was approved for use in 2000. A member of the oxazolidinone class …

Investigation of the effects of doping and post‐deposition treatments on the conductivity, morphology, and work function of poly (3, 4‐ethylenedioxythiophene)/poly …

J Huang, PF Miller, JS Wilson… - Advanced functional …, 2005 - Wiley Online Library
We investigate the influence of annealing conditions on the physical properties of thin films
of poly(3,4‐ethylenedioxythiophene)/poly(styrene sulfonate) (PEDOT/PSS). In particular, we …

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

…, CG Bergeron, SE Guilmain, PF Miller… - Nature …, 2018 - nature.com
… Paul F Miller … Reactions were stopped with sodium carbonate and OD 420 /OD 550
measurements were performed to determine promoter activity in Miller units. …

[HTML][HTML] Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity

…, M Momin, C Bergeron, A Fisher, PF Miller… - Nature …, 2020 - nature.com
Synthetic biology is a powerful tool to create therapeutics which can be rationally designed
to enable unique and combinatorial functionalities. Here we utilize non-pathogenic E coli …

Influence of thermal treatment on the conductivity and morphology of PEDOT/PSS films

J Huang, PF Miller, JC De Mello, AJ De Mello… - Synthetic Metals, 2003 - Elsevier
The electrical properties of conducting polymers are strongly dependent on their film
morphology and chemical and physical structure, which in turn can be strongly modified via a …

An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

…, KA West, AJ Degar, AM Brennan, PF Miller - Science translational …, 2019 - science.org
The intestine is a major source of systemic ammonia (NH 3 ); thus, capturing part of gut NH
3 may mitigate disease symptoms in conditions of hyperammonemia such as urea cycle …

Suppression of Ribosomal Reinitiation at Upstream Open Reading Frames in Amino Acid-Starved Cells Forms the Basis for GCN4 Translational Control

JP Abastado, PF Miller, BM Jackson… - Molecular and cellular …, 1991 - Taylor & Francis
GCN4 encodes a transcriptional activator of amino acid-biosynthetic genes in Saccharomyces
cerevisiae that is regulated at the translational level by upstream open reading frames (…

[HTML][HTML] The MarR Repressor of the Multiple Antibiotic Resistance (mar) Operon in Escherichia coli: Prototypic Member of a Family of Bacterial Regulatory Proteins …

MC Sulavik, LF Gambino, PF Miller - Molecular Medicine, 1995 - Springer
… β-Galactosidase assays were performed as described by Miller (25) using the chloroform-SDS
method of cell permeabilization. Briefly, cultures were grown in L broth to an A 600 = 0.3, …