User profiles for C. D. Howard

Christian D. Howard

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Cited by 2431

Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain

E Jašarević, CL Howerton, CD Howard… - Endocrinology, 2015 - academic.oup.com
The neonate is exposed to the maternal vaginal microbiota during parturition, providing the
primary source for normal gut colonization, host immune maturation, and metabolism. These …

Our milky way as a pure-disk galaxy—a challenge for galaxy formation

…, RM Rich, J Kormendy, CD Howard… - The Astrophysical …, 2010 - iopscience.iop.org
Bulges are commonly believed to form in the dynamical violence of galaxy collisions and
mergers. Here, we model the stellar kinematics of the Bulge Radial Velocity Assay (BRAVA) …

Early science with SOFIA, the stratospheric observatory for infrared astronomy

…, LA Helton, SD Horner, CD Howard… - The Astrophysical …, 2012 - iopscience.iop.org
The Stratospheric Observatory For Infrared Astronomy (SOFIA) is an airborne observatory
consisting of a specially modified Boeing 747SP with a 2.7 m telescope, flying at altitudes as …

The bulge radial velocity assay (BRAVA). II. Complete sample and data release

…, RM Rich, R De Propris, CD Howard… - The Astronomical …, 2012 - iopscience.iop.org
… We also present a rich new data set at b = −6 that complements the first results presented
in Howard et al. (2008, hereafter Paper I) and the properties of which conform to our other …

[HTML][HTML] Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner

E Jašarević, CD Howard, AM Misic, DP Beiting… - Scientific Reports, 2017 - nature.com
… OTUs were defined using 97% sequence similarity with CD-HIT, and a representative
sequence from each OTU containing ≥10 sequences was chosen for downstream analyses (…

The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus

E Jašarević, CD Howard, K Morrison, A Misic… - Nature …, 2018 - nature.com
Early prenatal stress disrupts maternal-to-offspring microbiota transmission and has lasting
effects on metabolism, physiology, cognition, and behavior in male mice. Here we show that …

[PDF][PDF] Genetic-based dissection unveils the inputs and outputs of striatal patch and matrix compartments

JB Smith, JR Klug, DL Ross, CD Howard, NG Hollon… - Neuron, 2016 - cell.com
The striatum contains neurochemically defined compartments termed patches and matrix.
Previous studies suggest patches preferentially receive limbic inputs and project to dopamine …

[PDF][PDF] Dynamic nigrostriatal dopamine biases action selection

CD Howard, H Li, CE Geddes, X Jin - Neuron, 2017 - cell.com
Dopamine is thought to play a critical role in reinforcement learning and goal-directed behavior,
but its function in action selection remains largely unknown. Here we demonstrate that …

[HTML][HTML] The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model

…, L Rutt, T Gyles, L Folts, KD Rock, CD Howard… - Nature …, 2021 - nature.com
Newborns are colonized by maternal microbiota that is essential for offspring health and
development. The composition of these pioneer communities exhibits individual differences, but …

Kinematics at the edge of the Galactic bulge: Evidence for cylindrical rotation

CD Howard, RM Rich, W Clarkson… - The Astrophysical …, 2009 - iopscience.iop.org
… At b = −8, we are at the point where the bulge density begins to drop sharply; our aim is to
search for subpopulations in these regions, and the signature of the inner halo (CD Howard et …