[HTML][HTML] Metabolic reprogramming in macrophages and dendritic cells in innate immunity
B Kelly, LA O'neill - Cell research, 2015 - nature.com
… more immune cells to the site of infection, and pro-inflammatory cytokines, which drive
further inflammation, and induce the adaptive immune response, which is mediated by T and B …
further inflammation, and induce the adaptive immune response, which is mediated by T and B …
Promoting cardiovascular health in the developing world: a critical challenge to achieve global health
BB Kelly, V Fuster - 2010 - books.google.com
Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations,
has emerged as a major health threat in developing countries. Cardiovascular disease …
has emerged as a major health threat in developing countries. Cardiovascular disease …
INFORMAS (I nternational N etwork for F ood and O besity/non‐communicable diseases R esearch, M onitoring and A ction S upport): overview and key principles
Non‐communicable diseases ( NCD s) dominate disease burdens globally and poor
nutrition increasingly contributes to this global burden. Comprehensive monitoring of food …
nutrition increasingly contributes to this global burden. Comprehensive monitoring of food …
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch
their core metabolism from oxidative phosphorylation to glycolysis 1 . Here we show that …
their core metabolism from oxidative phosphorylation to glycolysis 1 . Here we show that …
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans
…, KA Aaron, W Concepcion, JM Gardner, B Kelly… - Science, 2022 - science.org
Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …
Mental health in the COVID-19 pandemic
During any outbreak of an infectious disease, the population’s psychological reactions play
a critical role in shaping both spread of the disease and the occurrence of emotional distress …
a critical role in shaping both spread of the disease and the occurrence of emotional distress …
[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …
become more accurate as training sample sizes increase. The standard approach for …
Physics of graphite
BT Kelly - 1981 - inis.iaea.org
[en] This volume gives a thorough overview of the physics of graphite including structure,
thermal properties, mechanical properties, electronic properties, pore structure and the effects …
thermal properties, mechanical properties, electronic properties, pore structure and the effects …
Empirical asset pricing via machine learning
We perform a comparative analysis of machine learning methods for the canonical problem
of empirical asset pricing: measuring asset risk premiums. We demonstrate large economic …
of empirical asset pricing: measuring asset risk premiums. We demonstrate large economic …