Alzhemed: a potential treatment for Alzheimer's disease

PS Aisen, S Gauthier, B Vellas, R Briand… - Current Alzheimer …, 2007 - ingentaconnect.com
… drugs show γ-secretase modulating activity with reduction in amyloid accumulation in
transgenic mice [12], though tolerable doses may be insufficient for brain amyloid reduction; R-…

A Phase II study targeting amyloid-β with 3APS in mild-to-moderate Alzheimer disease

PS Aisen, D Saumier, R Briand, J Laurin, F Gervais… - Neurology, 2006 - AAN Enterprises
Background: As a potential disease-modifying treatment for Alzheimer disease (AD), 3-amino-1-propanesulfonic
acid (3APS) is a compound that binds to amyloid β (Aβ), a toxic protein …

Foundations of factor investing

J Bender, R Briand, D Melas… - Available at SSRN …, 2013 - papers.ssrn.com
Factor investing is based on the existence of factors that have earned a premium over long
periods, reflect exposure to systematic risk, and are grounded in the academic literature. …

Portfolio of risk premia: A new approach to diversification

J Bender, R Briand, F Nielsen… - Available at SSRN …, 2009 - papers.ssrn.com
The traditional asset allocation to equities and bonds is characterized by high volatility and
lacks sufficient diversification, particularly during periods of distress. The meltdown of 2001-…

Validation of radiation hardened designs by pulsed laser testing and SPICE analysis

V Pouget, D Lewis, H Lapuyade, R Briand… - Microelectronics …, 1999 - Elsevier
A new pulsed laser system dedicated to the simulation of radiation effects on integrated
circuits is presented. On-line testing capabilities are detailed and two SPICE models of …

Deploying multi-factor index allocations in institutional portfolios

J Bender, R Briand, D Melas, RA Subramanian… - Risk-Based and Factor …, 2015 - Elsevier
Bender et al. discussed six factors – value, low size, low volatility, high yield, quality and
momentum – that historically have earned a premium over long periods, represent exposure to …

LPV control of wind turbines for fatigue loads reduction using intelligent micro sensors

…, H Camblong, O Curea, R Briand - 2007 American Control …, 2007 - ieeexplore.ieee.org
This paper presents the first results of a research project leaded by LIPSI-ESTIA concerning
the association of intelligent micro sensors with advanced wind turbines (WTs) controllers to …

Energy model for the design of ultra-low power nodes for wireless sensor networks

G Terrasson, R Briand, S Basrour, V Dupé, O Arrijuria - Procedia Chemistry, 2009 - Elsevier
This article describes the modeling of a microsensor node for wireless sensor network
applications. Considering the heterogeneous aspect of a sensor node, the developed model …

[PDF][PDF] Integrating ESG into the investment process

R Briand, R Urwin, CP Chia - … , New York, NY, available at: www …, 2011 - top1000funds.com
In recent years, many institutional investors have been increasingly recognizing that the long-term
sustainability of their investments matters. Environmental, Social and Governance (…

High-performance liquid chromatographic determination of the lecithin/sphingomyelin ratio in amniotic fluid

RL Briand, S Harold, KG Blass - Journal of Chromatography B: Biomedical …, 1981 - Elsevier
A high-performance liquid chromatographic (HPLC) procedure has been developed for the
separation of phospholipids commonly found in amniotic fluid. The chromatographic …