Background Many patients with psoriatic arthritis have an inadequate response to tumor
necrosis factor (TNF) inhibitors. Guselkumab, a specific inhibitor of interleukin-23 (IL-23) via IL-…

Factor investing is based on the existence of factors that have earned a premium over long
periods, reflect exposure to systematic risk, and are grounded in the academic literature. …

Objective Guselkumab, a human monoclonal antibody specific to interleukin‐23p19,
demonstrated efficacy and safety versus placebo through week 24 of the phase III DISCOVER‐2 …

Objective Evaluation of the efficacy and safety of guselkumab, a human monoclonal antibody
targeting the interleukin-23p19 subunit, in patients with psoriatic arthritis (PsA) through 1 …

Objective The importance of early recognition of hemorrhagic shock and its effects on
outcome have long been recognized. Traditional vital signs are relatively insensitive as early …

Objectives Contrast‐induced acute kidney injury (CI‐AKI) is defined as either a 25% increase
in or an absolute elevation in serum creatinine (SCr) of 0.5 mg/ dL , 48 to 72 hours after …

Objective To test the diagnostic use of the triage white blood cell (WBC) count in differentiating
major from minor injuries. Methods We conducted a retrospective study of a prospectively …

Introduction: The influenza A 2009 (H1N1) virus is a pandemic respiratory infection commanding
international attention. More information is needed on patient demographics, illness …

Background Pandemic novel influenza A(H1N1) is a substantial threat and cause of
morbidity and mortality in the pregnant population. Methods We conducted an observational …

Bender et al. discussed six factors – value, low size, low volatility, high yield, quality and
momentum – that historically have earned a premium over long periods, represent exposure to …