Kidney toxicity is one of the most frequent adverse events reported during drug development.
The lack of accurate predictive cell culture models and the unreliability of animal studies …

… Values in parenthesis are the corresponding values of ΔG monomner (all energies in kJ
mol … 335 kJ mol −1 10 ). This is supported by an in situ 31 P NMR spectroscopic study of 1 in …

… a) is favoured by 225 kJ mol −1 , whereas dimerisation to the 1,3-dimer is favoured by 234
kJ mol −1 (making the 1,3-dimer slightly more favourable than the 1,2-dimer by 9 kJ mol −1 ). …

… = 20.4 kJ mol –1 in the case of 1a and 1b, ΔE = 4.6 kJ mol –1 in the case of 3a and 3b).
Heating a mixture of the isomers of 1 or 2 at reflux for ca. 30 min in toluene results in quantitative …

… this process (ΔG‡ = 83 kJ mol −1 ) is considerably greater than that observed previously in
the dimer [{P(μ-N t Bu)} 2 (OCH 2 C(Me) 2 CH 2 O)] 2 (ΔG‡ = 31 kJ mol −1 ), containing a far …

… oligomers of 2 at ΔG ‡ ≈ 43–45 kJ mol −1 , two distinct resonances for these environments
… The ΔG ‡ found for the oligomers of 2 compares to 31 kJ mol −1 found for the dimer [{P(μ-N t …

… kJ mol −1 ; 6: 54.1(±0.5) kJ mol −1 determined by 29 Si-NMR spectroscopy) [13]. An interesting
feature of the 29 Si-NMR spectra of the thallium compound 6 is the coupling with the 203/…

… Mary McPartlin … This may be interpreted as due to rapid exchange of the (THF) 2 Li +
fragment between the three equivalent bridging positions in 2 at high temperatures, the free …

… kJ mol-1) with that reported for AHex: (66.1 kJ mol-1),23 it seems that the intermediate
complex formation for this system follows the dissociative ion-pair mechanism 16-18 established …

We have previously developed a strategy for the preparation of heterometallic main-group
imido (RN2À) and phosphinidene (RP2À) compounds involving stepwise deprotonation of …