[HTML][HTML] Targeting foam cell formation to improve recovery from ischemic stroke
Inflammation is a crucial part of the healing process after an ischemic stroke and is required
to restore tissue homeostasis. However, the inflammatory response to stroke also worsens …
to restore tissue homeostasis. However, the inflammatory response to stroke also worsens …
[HTML][HTML] Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts
JC Zbesko, TVV Nguyen, T Yang, JB Frye… - Neurobiology of …, 2018 - Elsevier
Following stroke, the damaged tissue undergoes liquefactive necrosis, a stage of infarct
resolution that lasts for months although the exact length of time is currently unknown. One …
resolution that lasts for months although the exact length of time is currently unknown. One …
[HTML][HTML] Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue
TVV Nguyen, JB Frye, JC Zbesko, K Stepanovic… - Acta neuropathologica …, 2016 - Springer
This study provides a parallel characterization of the cytokine and chemokine response to
stroke in the human and mouse brain at different stages of infarct resolution. The study goal …
stroke in the human and mouse brain at different stages of infarct resolution. The study goal …
[HTML][HTML] Repeated administration of 2-hydroxypropyl-β-cyclodextrin (HPβCD) attenuates the chronic inflammatory response to experimental stroke
DA Becktel, JC Zbesko, JB Frye, AG Chung… - Journal of …, 2022 - Soc Neuroscience
Globally, more than 67 million people are living with the effects of ischemic stroke. Importantly,
many stroke survivors develop a chronic inflammatory response that may contribute to …
many stroke survivors develop a chronic inflammatory response that may contribute to …
Liquefaction of the brain following stroke shares a similar molecular and morphological profile with atherosclerosis and mediates secondary neurodegeneration in an …
AG Chung, JB Frye, JC Zbesko, E Constantopoulos… - eneuro, 2018 - eneuro.org
Here we used mouse models of heart and brain ischemia to compare the inflammatory
response to ischemia in the heart, a protein rich organ, to the inflammatory response to ischemia …
response to ischemia in the heart, a protein rich organ, to the inflammatory response to ischemia …
[HTML][HTML] IgA natural antibodies are produced following T-cell independent B-cell activation following stroke
JC Zbesko, JB Frye, DA Becktel, DK Gerardo… - Brain, behavior, and …, 2021 - Elsevier
Up to 30% of stroke patients experience cognitive decline within one year of their stroke.
There are currently no FDA-approved drugs that can prevent post-stroke cognitive decline, in …
There are currently no FDA-approved drugs that can prevent post-stroke cognitive decline, in …
[HTML][HTML] Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia
TVV Nguyen, M Hayes, JC Zbesko, JB Frye… - Acta neuropathologica …, 2018 - Springer
The goal of this study was to determine the chronic impact of stroke on the manifestation of
Alzheimer’s disease (AD) related pathology and behavioral impairments in mice. To …
Alzheimer’s disease (AD) related pathology and behavioral impairments in mice. To …
Post-stroke administration of the p75 neurotrophin receptor modulator, LM11A-31, attenuates chronic changes in brain metabolism, increases neurotransmitter levels …
…, KE Calderon, FG Garcia, JC Zbesko… - … of Pharmacology and …, 2022 - ASPET
The aim of this study was to test whether poststroke oral administration of a small molecule
p75 neurotrophin receptor (p75 NTR ) modulator (LM11A-31) can augment neuronal survival …
p75 neurotrophin receptor (p75 NTR ) modulator (LM11A-31) can augment neuronal survival …
Determinants of performance in the bull market
J Zbesko - Journal of Portfolio Management, 1989 - search.proquest.com
An attempt is made to quantify the determinants of relative equity performance over the 1980
bull market by examining multiple measures of performance derived as time series. Eight …
bull market by examining multiple measures of performance derived as time series. Eight …
Investigating the Chronic Inflammatory Response to Stroke: The Role of Glial Scar Astrocytes and B-Lymphocytes
J Zbesko - 2020 - search.proquest.com
Stroke affects nearly 800,000 Americans every year and, of survivors, around one third will
develop dementia. Not only personally devastating to sufferers, this disease places an …
develop dementia. Not only personally devastating to sufferers, this disease places an …