Lactoferricin: Lactoferricin: A lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties

JL Gifford, HN Hunter, HJ Vogel - Cellular and molecular life sciences, 2005 - Springer
The peptide lactoferricin (Lfcin) can be released from the multifunctional protein lactoferrin (LF)
through proteolysis by pepsin under acidic conditions, a reaction that occurs naturally in …

A systematic review of animal models of NAFLD finds high‐fat, high‐fructose diets most closely resemble human NAFLD

YR Im, H Hunter, D de Gracia Hahn, A Duret… - …, 2021 - Wiley Online Library
Background and Aims Animal models of human disease are a key component of translational
hepatology research, yet there is no consensus on which model is optimal for NAFLD. …

[HTML][HTML] Solution NMR studies of amphibian antimicrobial peptides: linking structure to function?

EF Haney, HN Hunter, K Matsuzaki, HJ Vogel - Biochimica et Biophysica …, 2009 - Elsevier
The high-resolution three-dimensional structure of an antimicrobial peptide has implications
for the mechanism of its antimicrobial activity, as the conformation of the peptide provides …

Functional and Evolutionary Insights from the Genomes of Three Parasitoid Nasonia Species

…, HC Hunter IV, GDD Hurst, SN Jhangian, H Jiang… - Science, 2010 - science.org
We report here genome sequences and comparative analyses of three closely related
parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important …

Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial

…, M Uchiyama, H Blacklock, M Arat, J Griffin, H Hunter… - The Lancet, 2021 - thelancet.com
Background Isatuximab is an anti-CD38 monoclonal antibody approved in combination with
pomalidomide–dexamethasone and carfilzomib–dexamethasone for relapsed or refractory …

[HTML][HTML] The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis* 210

HN Hunter, DB Fulton, T Ganz, HJ Vogel - Journal of Biological Chemistry, 2002 - ASBMB
… Immediately after dissolution, a series of one-dimensional 1 H spectra were acquired
over the following 24 h. Twenty min after the first 1 H spectrum was acquired, a 1-h two-…

[PDF][PDF] Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia

…, G Standen, A Sternberg, J Cavenagh, H Hunter… - Cancer cell, 2011 - cell.com
The relationships between normal and leukemic stem/progenitor cells are unclear. We
show that in ∼80% of primary human CD34+ acute myeloid leukemia (AML), two expanded …

[HTML][HTML] The solution structures of the human β-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus

DJ Schibli, HN Hunter, V Aseyev, TD Starner… - Journal of Biological …, 2002 - ASBMB
The three human β-defensins, HBD1–3, are 33–47-residue, cationic antimicrobial proteins
expressed by epithelial cells. All three proteins have broad spectrum antimicrobial activity, …

Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a …

…, K Honkalehto, M Huben, J Huffman, H Hunter… - The Lancet …, 2019 - thelancet.com
Background As lenalidomide becomes increasingly established for upfront treatment of
multiple myeloma, patients refractory to this drug represent a population with an unmet need. …

The effect of core stability training on balance and mobility in ambulant individuals with multiple sclerosis: a multi-centre series of single case studies

…, P Cowan, C Finnigan, H Hunter… - Multiple Sclerosis …, 2010 - journals.sagepub.com
Background: Core stability training is popular in the management of people with multiple
sclerosis (MS); however, scientific evidence to support its effectiveness is scarce. Objective: To …