The evolutionarily conserved planar cell polarity (PCP) pathway (or noncanonical Wnt
pathway) drives several important cellular processes, including epithelial cell polarization, cell …

Circletail is one of only two mouse mutants that exhibit the most severe form of neural tube
defect (NTD), termed craniorachischisis. In this disorder, almost the entire brain and spinal …

Despite rapid advances in cardiovascular developmental genetics, the precise morphogenetic
processes that coordinate heart development, and the genes and signaling pathways that …

Loop-tail (Lp) mice develop double outlet right ventricle and aortic arch defects, and the
defects are caused by mutations in the Vangl2 gene. Vangl2 mRNA is found in the outflow tract …

Although in nearly 200 field treatments of producing oil wells polymers have effectively
reduced the WOR, not all such wells polymers have effectively reduced the WOR, not all such …

… of the CAT gene cassette were measured from E11.5 outflow tracts by quantitative real-time
PCR, as described in Phillips et al. Primer sequences were as described in Phillips et al. …

The Drosophila scribble gene regulates apical-basal polarity and is implicated in control of
cellular architecture and cell growth control. Mutations in mammalian Scrib (circletail; Crc …

Aims The definitive cardiac outflow channels have three components: the intrapericardial
arterial trunks; the arterial roots with valves; and the ventricular outflow tracts (OFTs). We …

During ageing molecular damage leads to the accumulation of several hallmarks of ageing
including mitochondrial dysfunction, cellular senescence, genetic instability and chronic …

Planar cell polarity (PCP) is the mechanism by which cells orient themselves in the plane of
an epithelium or during directed cell migration, and is regulated by a highly conserved …