User profiles for D. A. Levine

Douglas A Levine MD

NYU Langone Health
Verified email at nyumc.org
Cited by 85936

Heart disease and stroke statistics—2022 update: a report from the American Heart Association

…, SS Khan, BM Kissela, KL Knutson, DA Levine… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

…, JE Ho, R Kalani, DS Kazi, D Ko, DA Levine… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Rethinking ovarian cancer: recommendations for improving outcomes

…, SB Kaye, CJ Lord, E Lengyel, DA Levine… - Nature Reviews …, 2011 - nature.com
There have been major advances in our understanding of the cellular and molecular biology
of the human malignancies that are collectively referred to as ovarian cancer. At a recent …

[HTML][HTML] Inferring tumour purity and stromal and immune cell admixture from expression data

…, V Trevińo, H Shen, PW Laird, DA Levine… - Nature …, 2013 - nature.com
Infiltrating stromal and immune cells form the major fraction of normal cells in tumour tissue
and not only perturb the tumour signal in molecular studies but also have an important role in …

[HTML][HTML] Integrated genomic characterization of endometrial carcinoma

DA Levine… - Nature, 2013 - nature.com
We performed an integrated genomic, transcriptomic and proteomic characterization of 373
endometrial carcinomas using array- and sequencing-based technologies. Uterine serous …

[PDF][PDF] An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics

…, AD Cherniack, AJ Kovatich, CC Benz, DA Levine… - Cell, 2018 - cell.com
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic
annotation data along with multi-platform molecular profiles of more than 11,000 human tumors …

Absolute quantification of somatic DNA alterations in human cancer

…, BA Weir, R Beroukhim, D Pellman, DA Levine… - Nature …, 2012 - nature.com
We describe a computational method that infers tumor purity and malignant cell ploidy
directly from analysis of somatic DNA alterations. The method, named ABSOLUTE, can detect …

OncoKB: a precision oncology knowledge base

…, G Iyer, YY Janjigian, T Kaley, DA Levine… - JCO precision …, 2017 - ascopubs.org
Purpose With prospective clinical sequencing of tumors emerging as a mainstay in cancer
care, an urgent need exists for a clinical support tool that distills the clinical implications …

[HTML][HTML] Evaluating cell lines as tumour models by comparison of genomic profiles

S Domcke, R Sinha, DA Levine, C Sander… - Nature …, 2013 - nature.com
Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of
hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour …

Insufficient sleep in adolescents and young adults: an update on causes and consequences

…, WP Adelman, CC Breuner, DA Levine… - …, 2014 - publications.aap.org
Chronic sleep loss and associated sleepiness and daytime impairments in adolescence are
a serious threat to the academic success, health, and safety of our nation’s youth and an …