Consensus-based recommendations for the management of juvenile systemic sclerosis

…, C Pilkington, N Toplak, A Van Royen… - …, 2021 - academic.oup.com
Juvenile systemic sclerosis (JSSc) is a rare disease of childhood and currently no international
consensus exists with regard to its assessment and treatment. This SHARE (Single Hub …

European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis—the SHARE initiative

…, L McCann, C Pilkington, A Ravelli, A van Royen… - …, 2019 - academic.oup.com
Objectives IgA vasculitis (IgAV, formerly known as Henoch–Schönlein purpura) is the most
common cause of systemic vasculitis in childhood. To date, there are no internationally …

Consensus-based recommendations for the management of juvenile localised scleroderma

…, R Russo, N Toplak, A Van Royen… - Annals of the …, 2019 - ard.bmj.com
In 2012, a European initiative called Single Hub and Access point for paediatric
Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic and …

European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides–the SHARE initiative

…, L McCann, C Pilkington, A Ravelli, A van Royen… - …, 2019 - academic.oup.com
Objectives The European initiative Single Hub and Access point for paediatric Rheumatology
in Europe (SHARE) aimed to optimize care for children with rheumatic diseases. Systemic …

Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells

…, F Broere, A van Royen… - Blood, The Journal …, 2016 - ashpublications.org
Autologous hematopoietic stem cell transplantation (HSCT) is increasingly considered for
patients with severe autoimmune diseases whose prognosis is poor with standard treatments. …

Autologous haemopoietic stem-cell transplantation in four patients with refractory juvenile chronic arthritis

N Wulffraat, A van Royen, M Bierings, J Vossen, W Kuis - The Lancet, 1999 - thelancet.com
Background Autologous haemopoietic stem-cell transplantation (AHSCT) had been
described as a possible treatment for severe autoimmune disease refractory to conventional …

Inflammatory mediators in human epilepsy: a systematic review and meta-analysis

…, KPJ Braun, A van Royen-Kerkhof… - Neuroscience & …, 2016 - Elsevier
Background Accumulating evidence suggests a role for inflammation in the pathophysiology
of epilepsy. Methods We performed a systematic review and meta-analysis of studies that …

[HTML][HTML] Consensus-based recommendations for the management of juvenile dermatomyositis

…, LJ McCann, A van Royen-Kerkhof - Annals of the …, 2017 - ard.bmj.com
Background In 2012, a European initiative called Single Hub and Access point for pediatric
Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic …

[HTML][HTML] An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist

…, J Frenkel, A van Royen-Kerkhoff… - … England Journal of …, 2009 - Mass Medical Soc
Background Autoinflammatory diseases manifest inflammation without evidence of infection,
high-titer autoantibodies, or autoreactive T cells. We report a disorder caused by mutations …

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

…, BK Barham, HL Leavis, A van Royen-Kerkof… - Nature …, 2016 - nature.com
Systemic autoinflammatory diseases are driven by abnormal activation of innate immunity 1
. Herein we describe a new disease caused by high-penetrance heterozygous germline …