Nrf2 is the key transcription factor regulating the antioxidant response. Nrf2 signaling is
repressed by Keap1 at basal condition and induced by oxidative stress. Keap1 is recently …

Oxidative stress has been implicated in the etiology of neurodegenerative disease, cancer
and aging. Indeed, accumulation of reactive oxygen and nitrogen species generated by …

Abstract Development of cancer is a long-term and multistep process which comprises
initiation, progression, and promotion stages of carcinogenesis. Conceivably, it can be targeted …

Antioxidant foods and ingredients are an important component of the food industry. In the past,
antioxidants were used primarily to control oxidation and retard spoilage, but today many …

Chemoprevention is a cancer preventive strategy to inhibit, delay or reverse carcinogenesis
using naturally occurring or synthetic chemical agents. Numerous epidemiological studies …

The nuclear factor-erythroid 2-related factor 2 (Nrf2) plays a critical role in protecting various
tissues against inflammation, which is a potential risk factor for colorectal and other cancers. …

Sulforaphane (SFN) is a natural isothiocyanate that is present in cruciferous vegetables such
as broccoli and cabbage. Previous studies have shown that SFN is effective in preventing …

The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented challenges to …

The cancer-preventive activity of vitamin E has been studied. Whereas some epidemiological
studies have suggested a protective effect of vitamin E against cancer formation, many …

Carcinogenesis is a multi-step process which could be prevented by phytochemicals.
Phytochemicals from dietary plants and other plant sources such as herbs are becoming …