We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n
= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …

In addition to the antigen receptors, other molecules contribute to cell activation: first, by
functioning as coreceptors (eg, CD4, CD8, CD19/CD21); second, by increasing the avidity of the …

ZAP-70 is a cytoplasmic protein tyrosine kinase that plays a critical role in the events involved
in initiating T-cell responses by the antigen receptor. Here we review the structure of ZAP-…

The 2012 National Survey of Science and Mathematics Education was designed to provide
up-to-date information and to identify trends in the areas of teacher background and …

Protein tyrosine kinases (PTKs) play an integral role in T cell activation and differentiation.
Defects in the Src-family PTKs in mice and in T cell lines have resulted in variable defects in …

Most institutional and individual portfolios are very undiversified in real e state: many hold no
real estate at all, many have holdings highly concentrated in certain regions or types of real …

The attempt to understand the physics of the structure of stars and their change in time–their
evolution–has been bothering many physicists and astronomers ever since the last century. …

We provide tables of theoretical isochrones in several photometric systems. To this aim, the
following steps are followed: (1) first, we re-write the formalism for converting synthetic stellar …

Why is credit rationed? Perhaps the most basic tenet of economics is that market equilibrium
entails supply equalling demand; that if demand should exceed supply, prices will rise, …

Home equity insurance policies—policies insuring homeowners against declines in the
prices of their homes—would bear some resemblance both to ordinary insurance and to …